As filed with the Securities and Exchange Commission on July 13, 2023

 

Registration No. 333-      

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

 

 

FORM S-1

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

 

 

Apogee Therapeutics, Inc.

(Exact name of registrant as specified in its charter)

 

 

Delaware   2836   88-0588063
(State or other jurisdiction of
incorporation or organization)
 

(Primary Standard Industrial

Classification Code Number)

 

(I.R.S. Employer

Identification Number)

 

221 Crescent St., Building 17, Suite 102b

Waltham, MA 02453

(650) 394-5230

(Address, including zip code, and telephone number, including area code, of registrant’s principal executive offices)

 

 

Michael Henderson, M.D.

Chief Executive Officer

Apogee Therapeutics, Inc.

221 Crescent St., Building 17, Suite 102b

Waltham, MA 02453

(650) 394-5230

(Name, address, including zip code, and telephone number, including area code, of agent for service)

 

 

With copies to:

 

         

Ryan A. Murr

Branden C. Berns
Melanie E. Neary

Gibson, Dunn & Crutcher LLP

555 Mission Street, Suite 3000

San Francisco, CA 94105-0921

(415) 393-8373

     

Divakar Gupta
Charles S. Kim
Kristin VanderPas
Darah Protas

Cooley LLP

55 Hudson Yards

New York, NY 10001-2157

(212) 479-6000

 

 

Approximate date of commencement of proposed sale to the public: As soon as practicable after this registration statement becomes effective.

 

If any of the securities being registered on this form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the following box.  ¨

 

If this form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.  x 333-272831

 

If this form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.  ¨

 

If this form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.  ¨

 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act. (Check one):

 

Large accelerated filer ¨ Accelerated filer ¨
       
Non-accelerated filer x Smaller reporting company x
       
    Emerging growth company x

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.  ¨

 

 

This Registration Statement shall become effective upon filing with the Securities and Exchange Commission in accordance with Rule 462(b) under the Securities Act of 1933, as amended.

 

 

 

 

 

EXPLANATORY NOTE AND INCORPORATION BY REFERENCE

 

Pursuant to Rule 462(b) under the Securities Act of 1933, as amended, Apogee Therapeutics, Inc., a Delaware corporation (“Apogee”), is filing this registration statement with the Securities and Exchange Commission (the “SEC”). This registration statement relates to the public offering of securities contemplated by the Registration Statement on Form S-1 (File No. 333-272831) (the “Registration Statement”) filed by Apogee with the SEC on June 22, 2023, as amended on July 3, 2023 and July 10, 2023, which the SEC declared effective on July 13, 2023.

 

Apogee is filing this registration statement for the sole purpose of increasing the aggregate number of shares of common stock, par value $0.00001 per share, offered by Apogee by 2,328,750 shares, 303,750 of which are subject to purchase upon exercise of the underwriters’ option to purchase additional shares of Apogee’s common stock. The additional shares that are being registered for issuance and sale are in an amount and at a price that together represent no more than 20% of the maximum aggregate offering price set forth in Filing Fee Table (Exhibit 107) contained in the Registration Statement. The contents of the Registration Statement, including all amendments and exhibits thereto, are incorporated by reference herein.

 

The required opinion and consents are listed on the Exhibit Index attached hereto and filed herewith.

 

EXHIBIT INDEX

 

Exhibit
Number
  Description of Exhibit
   
5.1   Opinion of Gibson, Dunn & Crutcher LLP.
   
23.1   Consent of Independent Registered Public Accounting Firm.
   
23.2   Consent of Gibson, Dunn & Crutcher, LLP (included in Exhibit 5.1).
   
24.1   Power of Attorney (incorporated by reference to Exhibit 24.1 of the Registration Statement (Registration No. 333-272831) filed on June 22, 2023). 
     
107   Filing Fee Table

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Waltham, Commonwealth of Massachusetts, on this 13th day of July, 2023.

 

  Apogee Therapeutics, Inc.
     
  By: /s/ Michael Henderson, M.D.
    Michael Henderson, M.D.
    Director and Chief Executive Officer

 

Pursuant to the requirements of the Securities Act of 1933, as amended, this registration statement has been signed by the following persons in the capacities and on the dates set forth opposite their names.

 

Signature   Title   Date
     

/s/ Michael Henderson, M.D.

Michael Henderson, M.D.

 

Director and Chief Executive Officer

(principal executive officer)

  July 13, 2023
     

/s/ Jane Pritchett Henderson

Jane Pritchett Henderson

 

Chief Financial Officer

(principal financial and accounting officer)

  July 13, 2023
     

*

Peter Harwin

  Chair and Director   July 13, 2023
     

*

Jennifer Fox

  Director   July 13, 2023
     

*

Andrew Gottesdiener, M.D.

  Director   July 13, 2023
     

*

Tomas Kiselak

  Director   July 13, 2023
     

*

William Jones, Jr.

  Director   July 13, 2023
     

*

Nimish Shah

  Director   July 13, 2023

 

*By: /s/ Michael Henderson, M.D.  
 

Michael Henderson, M.D.

Attorney-in-fact

 

 

 

Exhibit 5.1

 

  
  
  
 Client: 06647-00002

 

July 13, 2023

 

Apogee Therapeutics, Inc.
221 Crescent St., Building 17, Suite 102b
Waltham, MA 02453

 

Re:Apogee Therapeutics, Inc.
Registration Statement on Form S 1

 

Ladies and Gentlemen:

 

We have examined the Registration Statement on Form S-1 of Apogee Therapeutics, Inc., a Delaware corporation (the “Company”), filed with the Securities and Exchange Commission (the “Commission”) on the date hereof pursuant to Rule 462(b) (the “Additional Registration Statement”) promulgated under the Securities Act of 1933, as amended (the “Securities Act”), in connection with the offering by the Company of up to 2,328,750 shares (which includes shares that may be sold upon exercise of the underwriters’ option to purchase additional shares) of the Company’s common stock (the “Common Stock”), par value $0.00001 per share (the “Shares”). The Additional Registration Statement incorporates by reference the Registration Statement on Form S-1, File No. 333-272831, as amended (the “Registration Statement”), of the Company, filed with the Commission pursuant to the Securities Act.

 

In arriving at the opinion expressed below, we have examined originals, or copies certified or otherwise identified to our satisfaction as being true and complete copies of the originals, of specimen Common Stock certificates and such other documents, corporate records, certificates of officers of the Company and of public officials and other instruments as we have deemed necessary or advisable to enable us to render the opinions set forth below. In our examination, we have assumed without independent investigation the genuineness of all signatures, the legal capacity and competency of all natural persons, the authenticity of all documents submitted to us as originals and the conformity to original documents of all documents submitted to us as copies.

 

Based upon the foregoing, and subject to the assumptions, exceptions, qualifications and limitations set forth herein, we are of the opinion that the Shares, when issued against payment therefor as set forth in the Registration Statement, will be validly issued, fully paid and non-assessable.

 

We consent to the filing of this opinion as an exhibit to the Additional Registration Statement, and we further consent to the use of our name under the caption “Legal Matters” in the Registration Statement and the prospectus that forms a part thereof, which are incorporated by reference into the Additional Registration Statement. In giving these consents, we do not thereby admit that we are within the category of persons whose consent is required under Section 7 of the Securities Act or the Rules and Regulations of the Commission.

 

Very truly yours,

 

/s/ Gibson, Dunn & Crutcher LLP

 

Abu Dhabi Beijing Brussels Century City Dallas Denver Dubai Frankfurt Hong Kong Houston London Los Angeles
Munich
New York Orange County Palo Alto Paris San Francisco Singapore Washington, D.C.

 

 

 

Exhibit 23.1

 

Consent of Independent Registered Public Accounting Firm

 

We consent to the incorporation by reference in the Registration Statement on Form S-1 filed pursuant to Rule 462(b) of the Securities Act of 1933 of the reference to our firm under the caption “Experts” and to the incorporation by reference of our report dated April 28, 2023, with respect to the consolidated financial statements of Apogee Therapeutics, LLC included in Amendment No. 2 to the Registration Statement (Form S-1 No. 333-272831), and related Prospectus of Apogee Therapeutics, Inc. for the registration of its common stock.

 

/s/ Ernst & Young LLP

 

Boston, Massachusetts

July 13, 2023

 

 

 

Exhibit 107

 

Calculation of Filing Fee Tables

 

Form S-1MEF

(Form Type)

 

Apogee Therapeutics, Inc.

(Exact Name of Registrant as Specified in its Charter)

 

Table 1: Newly Registered Securities

 

  Security
Type
Security Class Title Fee Calculation
or Carry
Forward Rule
Amount
Registered
Proposed
Maximum
Offering
price Per
Unit
Maximum
Aggregate
Offering
Price(1)(2)
Fee Rate Amount of
Registration
Fee
Fees to be Paid Equity Common Stock, par value $0.00001 Rule 457(a) 2,328,750 $17.00 $39,588,750 0.00011020 $4,362.68
  Total Offering Amounts $39,588,750 0.00011020 $4,362.68
  Total Fees Previously Paid $0
  Total Fee Offsets $0
  Net Fee Due $4,362.68

 

(1)Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(a) under the Securities Act of 1933, as amended.

(2)Includes shares subject to the underwriters’ option to purchase additional shares, if any. Does not include the securities that the registrant previously registered on the Registration Statement on Form S-1, as amended (File No. 333-272831).