Publications | Apogee Therapeutics, Inc.

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APG777, anti-IL-13 monoclonal antibody, demonstrates extended half-life and sustained inhibition of Type 2 inflammatory biomarkers

Authors: Xiu Qin Lim, Erica Winter, Kristine Nograles, Sai Thankamony, Lukas Dillinger, Carl Dambkowski American College of Allergy, Asthma & Immunology’s (ACAAI) 2024 Annual Scientific Meeting, Boston, MA, USA, 24-28 October 2024.

Prolonged half-life and sustained inhibition of key inflammatory biomarkers: a phase 1 study of APG777, a high-affinity humanized IgG1 monoclonal antibody targeting IL-13

Authors: Xiu Qin Lim, Erica Winter, Kristine Nograles, Sai Thankamony, Lukas Dillinger, Carl Dambkowski
Society of Investigative Dermatology (SID) Annual Meeting, Dallas, TX, USA, 15–18 May, 2024

APG777, a high-affinity humanized IgG1 monoclonal antibody targeting IL-13, demonstrates prolonged half-life and pSTAT6 inhibition in non-human primates

Authors: Eric Zhu, Jason Oh, Lukas Dillinger, and Hussam Shaheen
Society of Investigative Dermatology (SID) Annual Meeting, Dallas, TX, USA, 15–18 May, 2024

APG808, a high-affinity fully human IgG1 monoclonal antibody targeting IL-4Rα, demonstrates prolonged half-life in non-human primates

Authors: Lukas Dillinger, Grant Wickman, Rebecca Dabora, Hussam Shaheen, Jason Oh, Eric Zhu
ATS 2024 International Conference, San Diego, CA, USA, 17–22 May 2024

APG808, a fully human monoclonal IgG1 antibody, binds to IL-4Rα with high affinity and blocks IL-13 and IL-4 mediated signaling in multiple in vitro assays

Authors: Lukas Dillinger, Grant Wickman, Rebecca Dabora, Hussam Shaheen, Jason Oh, Eric Zhu
ATS 2024 International Conference, San Diego, CA, USA, 17–22 May 2024

APG777, a high-affinity humanized IgG1 mAb targeting IL-13, demonstrates prolonged half-life in non-human primates

Authors: Eric Zhu, Ph.D., Jason Oh, Ph.D., Carl Dambkowski, M.D. and Hussam Shaheen, Ph.D.
European Academy of Dermatology and Venereology (EADV), Berlin, Germany, 11–14 October 2023

APG777, a humanized IgG1 mAb, binds to IL-13 with high affinity and potently blocks IL-13 signaling in multiple in vitro assays

Authors: Eric Zhu, Ph.D., Hussam Shaheen, Ph.D, Carl Dambkowski, M.D. and Jason Oh, Ph.D.
European Academy of Dermatology and Venereology (EADV), Berlin, Germany, 11–14 October 2023